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A list of awesome tools for complex trait genetics.

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GitHub Stars
87
Curated Resources
14
Categories
3 hours ago
Last Refreshed
genetic architectureGenetic correlation (LD score derivatives/extensions)Model trait relationships beyond correlationColocalisation/finemapping of causal variantsGene prioritizationHLA specific toolsgene-level analysis (TWAS)SimulationGenomic data wranglingPolygenic scoresPharmacogenomicsGWAS result repositories (preferably with an API)Mendelian randomization result repositoriesOnline tools

Use this list with your AI agent

Add the Context Awesome MCP server to Claude, Cursor, or any MCP client, then ask:

"Show me univariate models (heritability/poligenicity/stratified/geneset enrichment etc) resources from awesome-complex-trait-genetics"

Installation instructions →

What's inside

genetic architecture

  • ACLRUnivariate models (heritability/poligenicity/stratified/geneset enrichment etc)

  • BOLT-LMM/BOLT-REML

  • GCTA

  • HAMSTAUnivariate models (heritability/poligenicity/stratified/geneset enrichment etc)

  • i-LDSCUnivariate models (heritability/poligenicity/stratified/geneset enrichment etc)

  • KGWAS

Model trait relationships beyond correlation

Colocalisation/finemapping of causal variants

gene-level analysis (TWAS)

GWAS result repositories (preferably with an API)

Showing a sample of 87 resources. View the full list on GitHub →